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House struggles to deal with this and, within the season-seven finale, drives his automobile into Cuddy’s living room in anger. As Lisa Edelstein left the show before season eight, after this incident Cuddy leaves the hospital and House never sees her again. A vital plot element is House’s use of Vicodin to manage ache, caused by an infarction within the quadriceps muscle of his proper leg five years before the present’s first season, which also forces him to use a cane. In the first-season 11th episode “Detox”, House admits he’s hooked on Vicodin …